Scientist – In Vivo Photometry and Physiology

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Job Description

MapLight Therapeutics is a clinical stage biotech company founded by Stanford professors that

focuses on drug discovery for central nervous system disorders. We combine cutting-edge

technologies including optogenetics, in vivo photometry, and single-cell transcriptomics to identify

novel drug targets and develop effective therapies to address psychiatric symptoms. We are

seeking a highly motivated Scientist with expertise in optical methods for monitoring and

manipulating in vivo neural circuits who will become a key contributor to our discovery team. This

is a fantastic opportunity to join a small team and translate knowledge about brain circuitry into

transformative therapies.



Specific responsibilities include, but are not limited to:

• In vivo Ca2+ photometry, analysis and data interpretation

• Optogenetics and stereotaxic surgery for virus injection/cannula implantation

• Behavioral characterization in mouse relevant to CNS indications

• Behavioral pharmacology and drug administration

• Immunohistochemistry and confocal imaging



• PhD from an accredited university in a discipline related to neuroscience with

significant industry and/or academic lab experience

• Ability to lead and carry out experiments independently

• Experience with in vivo calcium photometry and analysis is necessary

• Experience with optogenetics, in vivo physiology, and mouse models of psychiatric

disorders is highly desired

• Strong working familiarity with rodent brain anatomy and functional neural circuitry

• Must work cooperatively in a goal-oriented team environment

• Strong oral and written communication skills to interact with all levels of management,

technical and scientific personnel

• Passion to contribute to the success of a cutting-edge company


MapLight Therapeutics is an Equal Opportunity Employer offering a competitive salary and

benefits package.

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