Scientist – In Vivo Photometry and Physiology

MapLight Therapeutics is an Equal Opportunity Employer offering a competitive salary and benefits package.


MapLight Therapeutics is a clinical stage biotech company founded by Stanford professors that focuses on drug discovery for central nervous system disorders. We combine cutting-edge technologies including optogenetics, in vivo photometry, and single-cell transcriptomics to identify novel drug targets and develop effective therapies to address psychiatric symptoms. We are seeking a highly motivated Scientist with expertise in optical methods for monitoring and manipulating in vivo neural circuits who will become a key contributor to our discovery team. This is a fantastic opportunity to join a small team and translate knowledge about brain circuitry into transformative therapies.

Specific responsibilities include, but are not limited to:
  • In vivo Ca2+ photometry, analysis and data interpretation
  • Optogenetics and stereotaxic surgery for virus injection/cannula implantation
  • Behavioral characterization in mouse relevant to CNS indications
  • Behavioral pharmacology and drug administration
  • Immunohistochemistry and confocal imaging
Specific responsibilities include, but are not limited to:
  • PhD from an accredited university in a discipline related to neuroscience with significant industry and/or academic lab experience
  • Ability to lead and carry out experiments independently
  • Experience with in vivo calcium photometry and analysis is necessary
  • Experience with optogenetics, in vivo physiology, and mouse models of psychiatric disorders is highly desired
  • Strong working familiarity with rodent brain anatomy and functional neural circuitry
  • Must work cooperatively in a goal-oriented team environment
  • Strong oral and written communication skills to interact with all levels of management, technical and scientific personnel
  • Passion to contribute to the success of a cutting-edge company

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