Find a trial near you
MapLight Therapeutics is recruiting patients for IRIS, a Phase 2 clinical trial evaluating ML-004, the company’s lead clinical compound for patients with Autism Spectrum Disorder. The study will assess whether there is an impact of ML-004 treatment on the core social communication deficits and on the associated features of irritability in ASD.
The randomized, double blind, placebo-controlled study will evaluate the efficacy and safety profile of ML-004 in up to 150 adults and adolescents with ASD. The study will be conducted in the United States, Australia, and Canada, and is fully funded by MapLight.
For more details on the study, and to contact participating sites near you, visit the study page at ClinicalTrials.gov.
Study Sites Currently Screening and Enrolling Patients
| Country | State / City | Physician | Institute |
|---|---|---|---|
| United States | Alabama / Dothan | Nelson Handal-Thome, MD | Harmonex Neuroscience Research |
| United States | Arizona / Phoenix | Christopher Smith, PhD | Southwest Autism Research & Resource Center |
| United States | California / San Francisco | Robert Hendren, DO | University of California, San Francisco |
| United States | Washington DC | Adelaide Robb, MD | Children's National Health System |
| United States | Florida / Orlando | Morteza Nadjafi, MD | APG Research, LLC |
| United States | Florida / Tampa | Daniel Fallon, MD | USF Psychiatry and Behavioral Neurosciences |
| United States | Illinois / Naperville | Riaz Baber, MD | AMR-Baber Research Inc |
| United States | Massachusetts / Lexington | Christopher Keary, MD | Mass General Hospital's Lurie Center for Autism |
| United States | Michigan / Bloomfield Hills | Richard Jackson, MD | Neurobehavioral Medicine Group |
| United States | Missouri / Columbia | Benjamin Black, MD | U. Missouri, Thompson Center for Autism & Neurodevelopmental Disorders |
| United States | New Jersey / Berlin | Steve Glass, MD | Hassman Research Institute |
| United States | New York / Staten Island | Matt DiBuono, MD | Richmond Behavioral Associates |
| United States | Pennsylvania / Media | Shivkumar Hatti, MD | Suburban Research Associates |
| United States | Texas / Houston | Lawrence Ginsberg, MD | Red Oak Psychiatry Associates, PA |
| United States | Texas / San Antonio | Jerry Tomasovic, MD | Road Runner Research, Ltd. |
| United States | Utah / Draper | Reid Robinson, MD | Cedar Clinical Research |
| Australia | New South Wales / Camperdown | Adam Gaustella, Prof | Brain and Mind Centre |
| Australia | Queensland / South Brisbane | Helen Heussler, MBBS | Children's Health Queensland Hospital and Health Service |
| Australia | Queensland / South Brisbane | Catherine Franklin, MBBS | Mater Research |
| Australia | Victoria / Parkville | David Amor, MBBS | The Royal Children's Hospital, Murdoch Children's Research Institute |
| Canada | British Columbia / Kelowna | Euguene Okorie | OCT Research ULC |
