(S)VP, Medical Affairs

Who We Are:

MapLight Therapeutics is a clinical stage biotech company that focuses on drug discovery for central nervous system (CNS) disorders. We combine cutting-edge technologies including optogenetics, in vivo physiology, and spatial transcriptomics to identify novel drug targets and aim to develop safe and effective therapies to address neurologic and psychiatric conditions.

What You’ll Do:

In collaboration with executive leadership, the (S)VP, Medical Affairs defines the Medical Affairs cross-functional strategy for clinical stage assets, develops and refines Medical Affairs (MA) plans, policies and procedures, builds a best-in-class team, and sets annual goals while maintaining excellence in standards and practices. The SVP of Medical Affairs will be MapLight’s first medical affairs hire and as such will build MapLight’s medical affairs capability and team as the organization grows. The (S)VP, Medical Affairs will advance collaborations with key opinion leaders,  establish and execute on engagement plans with health care practitioners, research groups, centers of excellence, and patient advocacy groups. Provides thought leadership and tactical execution for publication planning, medical education, medical information, field medical liaisons, and continuing medical communication within compliance guidelines. Works closely with clinical development and regulatory professionals and cross-functional stakeholders. This position reports to MapLight’s Chief Medical Officer with initial dotted-line reporting to the Chief Commercial Officer.

The SVP, Global Medical Affairs must have the ability to maintain scientific credibility while being commercially supportive, to communicate scientific and clinical results and effectively respond to medical inquiries from internal and external stakeholders. Collaborates across the organization to drive long-term organizational objectives to support the mission to identify, develop and deliver life-changing therapies to people living with disorders of the CNS.

Key Responsibilities:

  • Possess a robust understanding of Medical Affairs responsibilities, encompassing data communication (publications, medical education, medical information, field medical), data generation (trials, real-world data, etc.), and compliance (pharmacovigilance, medical compliance) to facilitate effective partnerships with key stakeholders.
  • Build and manage a best-in-class team to support product strategy, development plans, market access, and evolving Medical Affairs capabilities; including management of budget and resource allocation
  • In collaboration with CMO and CCO, ensure the formulation of clear and effectively communicated strategies for each product, guiding the development of robust Medical Plans that enhance patient access and contribute to improved patient outcomes
  • Lead the creation and delivery of prompt, precise, and unbiased communication of clinical and scientific information, medical education and training initiatives to healthcare professionals, both proactively and in response to information requests. Maintain consistency with promotional compliance and regulatory standards.
  • Act as a clinical representative for MapLight, participating in key professional meetings and engaging with medical societies and physicians identified through MapLight’s Key Opinion Leader (KOL) engagement plan.
  • Contribute to the strategic development of MapLight’s congress and professional relations plan.
  • Broaden MapLight’s network and presence externally and strengthen scientific, academic, government affairs, and advocacy relationships in the schizophrenia, Alzheimer’s, and autism communities. Serve as a Subject Matter Expert in those domains.
  • Contribute to the development and execution of compliant commercial activities.
  • Collaborate closely with commercial and clinical development teams to draft target product profiles and anticipate life cycle management opportunities and publication strategies.
  • Establish and oversee a compliant unsolicited educational grants approval process, in collaboration with key stakeholders, from planning to reporting.
  • Establish and oversee an investigator initiated trial (IIT) process for reviewing and selecting investigator initiatives for funding.
  • Oversee the entire process, in collaboration with key stakeholders, from planning to reporting, of Phase IV postmarketing research initiatives.
  • Cultivate and maintain collaborative relationships with internal stakeholders, including the Commercial, Clinical Development, Regulatory, and Legal teams, to reinforce business strategy and achieve organizational goals successfully.
  • Develop, refine and implement all required Medical Affairs policies and procedures and SOPs.
  • Create current and future competitive advantages by understanding and addressing unmet needs in the market and demonstrating a deep understanding of the strategies of other companies with competing products in their pipeline or on the market.



  • Medical Doctorate (M.D.) degree or equivalent. Relevant therapeutic experience in an academic or hospital environment in Neurology/Psychiatry required.
  • 10+ years of Medical Affairs experience, with at least 5 years in a leadership/management role with a thorough understanding of the U.S. medical affairs dynamics
  • Excellent clinical judgment, strong organizational abilities, high credibility and significant leadership potential
  • Flexible in your approach and demeanor to align seamlessly with the changing demands of evolving circumstances
  • Demonstrated abilities to attract, develop and retain talent and to operate within a culture that fosters innovation and supports appropriate risk-taking
  • Meaningful executive presence and a motivational leadership style that inspires others, conveys sureness, and demonstrates passion for MapLight’s mission
  • Possess an imaginative mindset with the ability to break down business barriers/obstacles with grace and consideration for others
  • Demonstrated ability to develop meaningful external scientific, academic, and KOL relationships
  • Publication history within MapLight’s therapeutic areas of focus or closely related areas
  • Effective presentation skills to key stakeholders and key decision makers
  • Knowledge of clinical trial methodology, data analysis and interpretation, regulatory requirements governing clinical trials and experience in development strategy and the design of protocols.
  • Experience leading or significantly contributing to a cross-functionally developed asset and therapeutic area specific communications platform, external corporate messaging plan, and comprehensive publication strategy plan
  • Ability to view Medical Affairs from both a medical and business perspective; to engage heavily with the commercial team and maintain strong collaborative relationships

Preferred Qualifications

  • Experience leading a field medical science liaison (MSL) team or as an MSL
  • Extensive understanding of and experience in both the clinical aspects and business of neurology/ psychiatry, ideally within the schizophrenia or Alzheimer’s therapeutic areas with established network of relationships within the community
  • Demonstrated ability to lead a U.S. medical affairs organization and manage cross-functional teams
  • Global product team and/or experience within medical contributing to the development of product strategy preferred
  • Experience in Real World Evidence Studies preferred


  • May be required to travel up to 50% of the time.



MapLight is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.


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