Head of Biologics Discovery

MapLight Therapeutics is an Equal Opportunity Employer offering a competitive salary and benefits package.

MapLight Therapeutics is a clinical stage biotech company that focuses on drug discovery for central nervous system disorders. Our platform utilizes cutting-edge technologies including optogenetics, in vivo physiology, and spatial transcriptomics to execute a circuit-based approach to target discovery. We are seeking a highly motivated Head of Biologics Discovery with expertise in RNA, biologics, gene therapy, and small molecule modalities who will become a key leader of our therapeutic development programs. This position requires working within a collaborative environment to leverage the MapLight platform for target discovery and target validation. The ideal candidate will have a successful industry track record of developing preclinical biologics to address CNS disorders. This is a fantastic opportunity to join a small team and translate knowledge about brain circuitry into transformative therapies.

Specific responsibilities include, but are not limited to:

  • Lead and develop preclinical workflows in non-small molecule CNS therapeutics including gene therapy, RNA, and/or antibody therapeutics
  • Interact with leadership and scientific group heads to shape strategic direction and chart development milestones
  • Interact with neuroscientists, pharmacologists, and bioinformaticians for target identification
  • Target validation in preclinical mouse models of CNS disorders
  • Manage CROs and interface with external collaborators

Specific responsibilities include, but are not limited to:

  • PhD related to neurobiology with 5+ years of experience in biotech industry
  • Solid track record in molecular, cellular, and biochemical techniques
  • Expertise in RNA (e.g. ASO or siRNA) and/or antibody therapeutics
  • Strong organizational and leadership skills to drive projects forward and meet milestone goals
  • Strong working knowledge of neuronal subtypes and functional brain anatomy
  • Experience successfully managing direct reports
  • Strong communication skills to interact with all levels of management, technical, scientific and external personnel
  • Passion to contribute to the success of a cutting-edge company

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